PXD057095

PXD057095 is an original dataset announced via ProteomeXchange.

Title	Identification of MELK-interacting proteins in HEK293T cells using IP-MS
Description	To investigate the mechanism by which Maternal Embryonic Leucine Zipper Kinase (MELK) regulates the actin cytoskeleton and affects coronavirus infections, we performed an Immunoprecipitation-Mass Spectrometry (IP-MS) assay. The goal was to identify specific actin-binding proteins that interact with MELK. This dataset contains the identification of proteins co-immunoprecipitated with FLAG-tagged MELK compared to an Empty Vector (EV) control in HEK293T cells .
HostingRepository	PRIDE
AnnounceDate	2026-04-01
AnnouncementXML	Submission_2026-04-01_01:17:25.869.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kuai Yu
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2024-10-23 02:09:47	ID requested
⏵ 1	2026-04-01 01:17:26	announced

Dataset with its publication pending

submitter keyword: None

Kuai Yu
contact affiliation	Guangzhou Medical University
contact email	yukuaic@126.com
lab head
Kuai Yu
contact affiliation	Guangzhou Medical University
contact email	yukuaic@126.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD057095

PRIDE project URI

• PRIDE
  1. PXD057095
     1. Label: PRIDE project
     2. Name: Identification of MELK-interacting proteins in HEK293T cells using IP-MS