PXD057007

PXD057007 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteome of wild type and Nsun7 knockout mice testis
Description	Investigation of a new RNA-modification-based mechanism in mammalian spermatogenesis. We created a mice line devoid of testis-specific m5C RNA methyltransferase Nsun7. These mice demonstrated male infertility due to a peculiar defect in sperm tail assembly – mispositioning of the longitudinal columns of the fibrous sheath. The whole testis proteomes of wild type and Nsun7 knockout mice were obtained to study the molecular pathways affected by NSUN7.
HostingRepository	PRIDE
AnnounceDate	2025-03-07
AnnouncementXML	Submission_2025-03-07_07:05:16.388.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ekaterina Guseva
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-10-21 03:42:18	ID requested
⏵ 1	2025-03-07 07:05:16	announced

Publication List

10.1261/RNA.080320.124;

10.1261/RNA.080320.124;

Keyword List

submitter keyword: Testis, Nsun7, spermatogenesis, longitudinal columns, methyltransferase

submitter keyword: Testis, Nsun7, spermatogenesis, longitudinal columns, methyltransferase

Contact List

Petr Sergiev
contact affiliation	Lomonosov Moscow State University
contact email	petya@genebee.msu.ru
lab head
Ekaterina Guseva
contact affiliation	Lomonosov Moscow State University
contact email	eguseva98@mail.ru
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/03/PXD057007
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/03/PXD057007

PRIDE project URI

Repository Record List

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