PXD057007 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteome of wild type and Nsun7 knockout mice testis |
Description | Investigation of a new RNA-modification-based mechanism in mammalian spermatogenesis. We created a mice line devoid of testis-specific m5C RNA methyltransferase Nsun7. These mice demonstrated male infertility due to a peculiar defect in sperm tail assembly – mispositioning of the longitudinal columns of the fibrous sheath. The whole testis proteomes of wild type and Nsun7 knockout mice were obtained to study the molecular pathways affected by NSUN7. |
HostingRepository | PRIDE |
AnnounceDate | 2025-03-07 |
AnnouncementXML | Submission_2025-03-07_07:05:16.388.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Ekaterina Guseva |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-10-21 03:42:18 | ID requested | |
⏵ 1 | 2025-03-07 07:05:16 | announced | |
Publication List
Keyword List
submitter keyword: Testis, Nsun7, spermatogenesis, longitudinal columns, methyltransferase |
Contact List
Petr Sergiev |
contact affiliation | Lomonosov Moscow State University |
contact email | petya@genebee.msu.ru |
lab head | |
Ekaterina Guseva |
contact affiliation | Lomonosov Moscow State University |
contact email | eguseva98@mail.ru |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/03/PXD057007 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD057007
- Label: PRIDE project
- Name: Proteome of wild type and Nsun7 knockout mice testis