PXD056950 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Entamoeba histolytica nuclear proteome |
Description | The polyadenylation factor EhCFIm25 has been recently reported as a biochemical target in Entamoeba histolytica. The prediction and experimental characterization of its interactome revealed close relationships between proteins involved in gene expression regulation and enzymes of energy metabolism. Here, the identification of the nuclear proteome of E. histolytica by mass spectrometry analysis showed the presence of typically cytoplasmic proteins in the nuclear compartment, which could have moonlight functions. Prediction of PPI network confirmed the relevance of some metabolic enzymes in the coordination between energy and RNA metabolism, opening new perspectives for human amoebiasis control. |
HostingRepository | PRIDE |
AnnounceDate | 2025-06-09 |
AnnouncementXML | Submission_2025-06-08_16:11:02.526.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Rodolfo G Avila-Bonilla |
SpeciesList | scientific name: Entamoeba histolytica HM-1:IMSS-A; NCBI TaxID: 885318; |
ModificationList | No PTMs are included in the dataset |
Instrument | Synapt MS |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-10-18 07:27:39 | ID requested | |
⏵ 1 | 2025-06-08 16:11:03 | announced | |
Publication List
Avila-Bonilla RG, Vel, á, zquez Guzm, á, n JA, Ram, í, rez-Moreno E, Marchat LA, A network of RNA-binding and metabolic proteins evidenced in the Entamoeba histolytica nuclear proteome. Exp Parasitol, 274():108965(2025) [pubmed] |
10.1016/j.exppara.2025.108965; |
Keyword List
submitter keyword: Entamoeba histolytica |
Contact List
Laurence A. Marchat |
contact affiliation | lmarchat@gmail.com |
contact email | lmarchat@gmail.com |
lab head | |
Rodolfo G Avila-Bonilla |
contact affiliation | Instituto Politécnico Nacional |
contact email | avilab.r.g@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/06/PXD056950 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD056950
- Label: PRIDE project
- Name: Entamoeba histolytica nuclear proteome