PXD056950

PXD056950 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Entamoeba histolytica nuclear proteome
Description	The polyadenylation factor EhCFIm25 has been recently reported as a biochemical target in Entamoeba histolytica. The prediction and experimental characterization of its interactome revealed close relationships between proteins involved in gene expression regulation and enzymes of energy metabolism. Here, the identification of the nuclear proteome of E. histolytica by mass spectrometry analysis showed the presence of typically cytoplasmic proteins in the nuclear compartment, which could have moonlight functions. Prediction of PPI network confirmed the relevance of some metabolic enzymes in the coordination between energy and RNA metabolism, opening new perspectives for human amoebiasis control.
HostingRepository	PRIDE
AnnounceDate	2025-06-09
AnnouncementXML	Submission_2025-06-08_16:11:02.526.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Rodolfo G Avila-Bonilla
SpeciesList	scientific name: Entamoeba histolytica HM-1:IMSS-A; NCBI TaxID: 885318;
ModificationList	No PTMs are included in the dataset
Instrument	Synapt MS

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-10-18 07:27:39	ID requested
⏵ 1	2025-06-08 16:11:03	announced

Publication List

Avila-Bonilla RG, Vel, á, zquez Guzm, á, n JA, Ram, í, rez-Moreno E, Marchat LA, A network of RNA-binding and metabolic proteins evidenced in the Entamoeba histolytica nuclear proteome. Exp Parasitol, 274():108965(2025) [pubmed]
10.1016/j.exppara.2025.108965;

Avila-Bonilla RG, Vel, á, zquez Guzm, á, n JA, Ram, í, rez-Moreno E, Marchat LA, A network of RNA-binding and metabolic proteins evidenced in the Entamoeba histolytica nuclear proteome. Exp Parasitol, 274():108965(2025) [pubmed]

10.1016/j.exppara.2025.108965;

Keyword List

submitter keyword: Entamoeba histolytica

submitter keyword: Entamoeba histolytica

Contact List

Laurence A. Marchat
contact affiliation	lmarchat@gmail.com
contact email	lmarchat@gmail.com
lab head
Rodolfo G Avila-Bonilla
contact affiliation	Instituto Politécnico Nacional
contact email	avilab.r.g@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/06/PXD056950
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/06/PXD056950

PRIDE project URI

Repository Record List

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