PXD056926
PXD056926 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Fusing Engineered Bacterial Strains with NIR-II AIEgen for Multimodal Image-guided Phototherapy and Immunotherapy |
Description | we present an aggregation-induced emission (AIE) - bacteria hybrid bionic robot to address the above issues. This bionic robot is composed of a multifunctional AIE molecule, INX-2 and Escherichia coli Nissle 1917 (EcN), i.e. EcN@INX-2. The robot is characterized by NIR-II fluorescence emission with efficient photodynamic and photothermal effects and tumor targeting, which was realized by INX-2 and EcN respectively, EcN@INX-2 achieved in vivo multimodal imaging and therapy of the tumors through multiple mechanisms including the activation of anti-tumor immunity, photodynamic and photothermal therapy in CT26 tumor-bearing female mice. |
HostingRepository | iProX |
AnnounceDate | 2024-10-18 |
AnnouncementXML | Submission_2024-10-17_20:23:41.869.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Liwei Zhu |
SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
ModificationList | No PTMs are included in the dataset |
Instrument | timsTOF Pro |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2024-10-17 20:23:29 | ID requested | |
⏵ 1 | 2024-10-17 20:23:42 | announced |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Aggregation-induced emission, Bacteria, Bionic Robot, Phototheranostics, Immunotherapy |
Contact List
Ying Li | |
---|---|
contact affiliation | Guangzhou Medical University Innovation Research Center for AIE Pharmaceutical Biology |
contact email | liying@gzhmu.edu.cn |
lab head | |
Liwei Zhu | |
contact affiliation | Guangzhou Medical University Innovation Research Center for AIE Pharmaceutical Biology |
contact email | 337864188@qq.com |
dataset submitter |
Full Dataset Link List
iProX dataset URI |