PXD056760

PXD056760 is an original dataset announced via ProteomeXchange.

Title	Identification and characterization of the elusive protein backbone of the immuno-dominant and specific Em2(G11) metacestode antigen of Echinococcus multilocularis
Description	Alveolar echinococcosis (AE) caused by Echinococcus multilocularis is a severe zoonotic disease in humans. One of the major metacestode antigens of E. multilocularis is the Em2 or Em2(G11) native purified antigen. The main objective of the current study was to identify and characterize the elusive protein backbone of the specific and immuno-dominant Em2(G11) antigen of E. multilocularis. Two biological replicates were used. Following samples are submitted: European isolate (J2012) - Replicate 1 (Sample F284313): 20200127_08_J2012_1F.raw European isolate (J2012) - Replicate 2 (Sample F284314): 20200127_09_J2012_2F.raw Central Asian isolate (AT17) - Replicate 1 (Sample F284307): 20200127_10_AT17_1F.raw Central Asian isolate (AT17) - Replicate 2 (Sample F284308): 20200127_11_AT17_2F.raw
HostingRepository	PRIDE
AnnounceDate	2025-05-07
AnnouncementXML	Submission_2025-05-07_03:27:21.468.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD056760
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Ramon Eichenberger
SpeciesList	scientific name: Echinococcus multilocularis; NCBI TaxID: 6211;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2024-10-13 11:15:32	ID requested
⏵ 1	2025-05-07 03:27:22	announced

Kronenberg PA, Laurim, ä, e T, Reinehr M, Deibel A, Hasler S, Gehrig P, Weber A, Deplazes P, Eichenberger RM, . Front Parasitol, 4():1540215(2025) [pubmed]

10.3389/fpara.2025.1540215;

10.6019/PXD056760;

submitter keyword: proteomics,Em2, Em2(G11)

Ramon M.
contact affiliation	Medical Micro- & Molecular Biology Institute of Chemistry and Biotechnology Zurich University of Applied Sciences
contact email	ramon.eichenberger@zhaw.ch
lab head
Ramon Eichenberger
contact affiliation	Medical Micro- & Molecular Biology Institute of Chemistry and Biotechnology Zurich University of Appled Sciences
contact email	ramon.eichenberger@zhaw.ch
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD056760
     1. Label: PRIDE project
     2. Name: Identification and characterization of the elusive protein backbone of the immuno-dominant and specific Em2(G11) metacestode antigen of Echinococcus multilocularis