PXD056748
PXD056748 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Integrated Proteogenomic Characterization of Localized Prostate Cancer Identifies Biological Insights and Subtype-Specific Therapeutic Strategies |
Description | We profiled the genome, transcriptome, proteome and phosphoproteome of 145 cases of localized prostate cancer (PCa) in Chinese patients and revealed three subtypes with distinct molecular features. We integrated multi-omic data to refine molecular subtyping of localized PCa, and identified NANS as a potential prognostic biomarker and therapeutic option for aggressive PCa. |
HostingRepository | iProX |
AnnounceDate | 2024-10-23 |
AnnouncementXML | Submission_2025-04-15_01:22:04.305.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Xinxin Zhang |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Orbitrap Exploris 480 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2024-10-11 20:46:55 | ID requested | |
⏵ 1 | 2025-04-15 01:22:05 | announced |
Publication List
Ou W, Zhang XX, Li B, Tuo Y, Lin RX, Liu PF, Guo JP, Un HC, Li MH, Lei JH, Gao XJ, Zheng FF, Chen LW, Long LL, Wang ZR, Integrated proteogenomic characterization of localized prostate cancer identifies biological insights and subtype-specific therapeutic strategies. Nat Commun, 16(1):3189(2025) [pubmed] |
Keyword List
submitter keyword: prostate cancer, proteomics |
Contact List
Zongren Wang | |
---|---|
contact affiliation | The First Affiliated Hospital, Sun Yat-sen University |
contact email | wangzr27@mail.sysu.edu.cn |
lab head | |
Xinxin Zhang | |
contact affiliation | The First Affiliated Hospital, Sun Yat-sen University |
contact email | diluczhang@foxmail.com |
dataset submitter |
Full Dataset Link List
iProX dataset URI |