⮝ Full datasets listing

PXD056748

PXD056748 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleIntegrated Proteogenomic Characterization of Localized Prostate Cancer Identifies Biological Insights and Subtype-Specific Therapeutic Strategies
DescriptionWe profiled the genome, transcriptome, proteome and phosphoproteome of 145 cases of localized prostate cancer (PCa) in Chinese patients and revealed three subtypes with distinct molecular features. We integrated multi-omic data to refine molecular subtyping of localized PCa, and identified NANS as a potential prognostic biomarker and therapeutic option for aggressive PCa.
HostingRepositoryiProX
AnnounceDate2024-10-23
AnnouncementXMLSubmission_2025-04-15_01:22:04.305.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterXinxin Zhang
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Exploris 480
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-10-11 20:46:55ID requested
12025-04-15 01:22:05announced
Publication List
Ou W, Zhang XX, Li B, Tuo Y, Lin RX, Liu PF, Guo JP, Un HC, Li MH, Lei JH, Gao XJ, Zheng FF, Chen LW, Long LL, Wang ZR, Integrated proteogenomic characterization of localized prostate cancer identifies biological insights and subtype-specific therapeutic strategies. Nat Commun, 16(1):3189(2025) [pubmed]
Keyword List
submitter keyword: prostate cancer, proteomics
Contact List
Zongren Wang
contact affiliationThe First Affiliated Hospital, Sun Yat-sen University
contact emailwangzr27@mail.sysu.edu.cn
lab head
Xinxin Zhang
contact affiliationThe First Affiliated Hospital, Sun Yat-sen University
contact emaildiluczhang@foxmail.com
dataset submitter
Full Dataset Link List
iProX dataset URI