PXD056632

PXD056632 is an original dataset announced via ProteomeXchange.

Title	Quantitative profiling of STOichiometry by Resolvable Mass tags
Description	Post-translational modifications (PTMs) play important roles in modulating biological functions of proteins. Stoichiometry, which quantifies the modification percentage, is a critical factor for any given PTM. In this work, we developed a chemoproteomic strategy called “STO-MS” to systematically quantify the PTM stoichiometry in complex biological samples. This strategy employs a resolvable mass tag to differentiate proteoforms with different number of modifications, and utilizes liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) techniques to measure PTM stoichiometry at the proteomic level.
HostingRepository	iProX
AnnounceDate	2024-10-08
AnnouncementXML	Submission_2024-12-25_18:48:05.813.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yuan Liu
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2024-10-08 20:31:53	ID requested
1	2024-10-08 20:32:07	announced
⏵ 2	2024-12-25 18:48:06	announced	2024-12-26: Add Publication.

Chen Y, Quan B, Li Y, Liu Y, Qin W, Wang C, Quantitative profiling of PTM stoichiometry by resolvable mass tags. RSC Chem Biol, 3(11):1320-1324(2022) [pubmed]

submitter keyword: PTM, stoichiometry

Chu Wang
contact affiliation	Peking University
contact email	chuwang@pku.edu.cn
lab head
Yuan Liu
contact affiliation	Peking University
contact email	wendao@pku.edu.cn
dataset submitter

iProX dataset URI