PXD056581
PXD056581 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomics analysis for liver from WT and Hsd17b6 liver specific knockout mice |
| Description | Eight weeks old LSL-Cas9 mice were injected with AAV2/8 expressing Cre driving by TBG promoter and sgRNA of gene of interest to specifically knockout gene in liver. In the present study, either control or sgHsd17b6 virus are injected. The mice are subjected to high fat choline dificient diet feeding for 8 weeks and then the liver samples were collected and subjected to Astral-DIA based proteomics analysis. |
| HostingRepository | iProX |
| AnnounceDate | 2024-10-02 |
| AnnouncementXML | Submission_2025-09-03_00:17:23.709.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Anyuan He |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Astral |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-10-08 00:16:17 | ID requested | |
| ⏵ 1 | 2025-09-03 00:17:24 | announced |
Publication List
| Yuan D, Bai N, Zhu Q, Song S, He A, Wang J, Chen Y, Hepatic HSD17B6 is dispensable for diet-induced fatty liver disease in mice. Biochem Biophys Rep, 41():101924(2025) [pubmed] |
Keyword List
| submitter keyword: Mouse, Hsd17b6, MASH |
Contact List
| Anyuan He | |
|---|---|
| contact affiliation | Anhui Medical University |
| contact email | heanyuan85@foxmail.com |
| lab head | |
| Anyuan He | |
| contact affiliation | Anhui Medical University |
| contact email | heanyuan85@foxmail.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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