PXD056431

PXD056431 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Ward_2024_VS1_ Mapping C. difficile TcdB interactions with host proteins by BioID
Description	This dataset consists of 41 raw mass spectrometry files and associated peak lists and results files, acquired on a Thermo Orbitrap Exploris 480 operated in Data-Dependent Acquisition mode. Protein affinity purification was performed by Jennifer Ward, while Jennifer Ward and John Tam generated samples. Mass spectrometric acquisition was performed by Karl Schreiber. Analysis was performed by Jennifer Ward, Karl Schreiber, Ji-Young Youn, and Roman Melnyk. The files are associated with a manuscript by Jennifer Ward et al. that uses proximity-dependent biotinylation approaches to identify host targets of Diphtheria Toxin (DT) and the Clostridioides difficile toxin B (TcdB). Roman Melnyk is the corresponding author for the manuscript and should be contacted for questions regarding this dataset (roman.melnyk@sickkids.ca).
HostingRepository	MassIVE
AnnounceDate	2025-01-01
AnnouncementXML	Submission_2025-01-01_03:32:30.743.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Ji-Young Youn
SpeciesList	scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationList	L-methionine sulfoxide; N-acetylated residue
Instrument	Orbitrap Exploris 480

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-10-01 10:36:30	ID requested
⏵ 1	2025-01-01 03:32:31	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: Affinity purification, BioID, Proximity-dependent biotinylation, Protein-protein interaction, Diphtheria Toxin, Clostridioides difficile toxin B

submitter keyword: Affinity purification, BioID, Proximity-dependent biotinylation, Protein-protein interaction, Diphtheria Toxin, Clostridioides difficile toxin B

Contact List

Ji-Young Youn
contact affiliation	Hospital for Sick Children
contact email	jiyoung.youn@sickkids.ca
lab head
Ji-Young Youn
contact affiliation	Hospital for Sick Children
contact email	jiyoung.youn@sickkids.ca
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v08/MSV000096003/

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v08/MSV000096003/