PXD056130

PXD056130 is an original dataset announced via ProteomeXchange.

Title	ANXA1 binds and stabilizes EGFR to promote nasopharyngeal carcinoma radioresistance
Description	To search proteins that interact with EGFR, EGFR interactors were coimmunoprecipitated with anti-EGFR antibody from 5-8F cell extracts, separated on SDS-PAGE and stained with Coomassie blue, and non-immune IgG antibody instead of anti-EGFR antibody served as control. Interested bands were excised, and subjected to in gel trypsin digestion and liquid chromatography and high-throughput mass spectrometry (LC-MS/MS) analysis.As a result, a total of 268 proteins including ANXA1 and CBL were identified .
HostingRepository	iProX
AnnounceDate	2024-09-18
AnnouncementXML	Submission_2024-12-22_19:43:04.716.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Shanshan Lu
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2024-09-23 23:57:48	ID requested
1	2024-09-23 23:58:24	announced
⏵ 2	2024-12-22 19:43:05	announced	2024-12-23: Add Publication.

Feng J, Lu SS, Xiao T, Huang W, Yi H, Zhu W, Fan S, Feng XP, Li JY, Yu ZZ, Gao S, Nie GH, Tang YY, Xiao ZQ, ANXA1 Binds and Stabilizes EphA2 to Promote Nasopharyngeal Carcinoma Growth and Metastasis. Cancer Res, 80(20):4386-4398(2020) [pubmed]

submitter keyword: ANXA1, EGFR, stability,nasopharyngeal carcinoma, radioresistance

Zhiqiang Xiao
contact affiliation	Research Center of Carcinogenesis and Targeted Therapy, Xiangya Hospital, Central South University
contact email	zqxiao2001@hotmail.com
lab head
Shanshan Lu
contact affiliation	Research Center of Carcinogenesis and Targeted Therapy, Xiangya Hospital, Central South University
contact email	susan880102@163.com
dataset submitter

iProX dataset URI