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PXD056130

PXD056130 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleANXA1 binds and stabilizes EGFR to promote nasopharyngeal carcinoma radioresistance
DescriptionTo search proteins that interact with EGFR, EGFR interactors were coimmunoprecipitated with anti-EGFR antibody from 5-8F cell extracts, separated on SDS-PAGE and stained with Coomassie blue, and non-immune IgG antibody instead of anti-EGFR antibody served as control. Interested bands were excised, and subjected to in gel trypsin digestion and liquid chromatography and high-throughput mass spectrometry (LC-MS/MS) analysis.As a result, a total of 268 proteins including ANXA1 and CBL were identified .
HostingRepositoryiProX
AnnounceDate2024-09-18
AnnouncementXMLSubmission_2024-09-23_23:58:24.462.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterShanshan Lu
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-09-23 23:57:48ID requested
12024-09-23 23:58:24announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: ANXA1,EGFR, stability,nasopharyngeal carcinoma, radioresistance
Contact List
Zhiqiang Xiao
contact affiliationResearch Center of Carcinogenesis and Targeted Therapy, Xiangya Hospital, Central South University
contact emailzqxiao2001@hotmail.com
lab head
Shanshan Lu
contact affiliationResearch Center of Carcinogenesis and Targeted Therapy, Xiangya Hospital, Central South University
contact emailsusan880102@163.com
dataset submitter
Full Dataset Link List
iProX dataset URI