PXD056092

PXD056092 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Ethanol Exposure during Differentiation of Human Induced Pluripotent Stem Cells Reduces Cardiomyocyte Generation and Alters Metabolism
Description	In this study, we investigated the effects of ethanol exposure on cardiomyocyte differentiation by treating the cells with various concentrations of ethanol. The results indicated that ethanol exposure during hiPSC-CM differentiation reduced cell viability, cell proliferation, and cardiomyocyte yield, and caused mitochondrial dysfunction, redox imbalance, and changes of proteomic profiles.
HostingRepository	PRIDE
AnnounceDate	2025-05-23
AnnouncementXML	Submission_2025-05-23_08:59:30.860.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Longping Fu
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Exploris 480

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-09-23 07:34:34	ID requested
⏵ 1	2025-05-23 08:59:31	announced

Publication List

Man K, Fu L, Lane A, Harris F, Reid O, Armand LC, Forghani P, Wu R, Faundez V, Brown LA, Xu C, Ethanol exposure during differentiation of human induced pluripotent stem cells reduces cardiomyocyte generation and alters metabolism. Life Sci, 364():123434(2025) [pubmed]
10.1016/j.lfs.2025.123434;

Man K, Fu L, Lane A, Harris F, Reid O, Armand LC, Forghani P, Wu R, Faundez V, Brown LA, Xu C, Ethanol exposure during differentiation of human induced pluripotent stem cells reduces cardiomyocyte generation and alters metabolism. Life Sci, 364():123434(2025) [pubmed]

10.1016/j.lfs.2025.123434;

Keyword List

submitter keyword: cardiomyocyte differentiation, ethanol treatment

submitter keyword: cardiomyocyte differentiation, ethanol treatment

Contact List

Ronghu Wu
contact affiliation	Georgia Institute of Technology
contact email	ronghu.wu@chemistry.gatech.edu
lab head
Longping Fu
contact affiliation	Georgia Institute of Technology
contact email	lpfu46@gatech.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD056092
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD056092

PRIDE project URI

Repository Record List

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