PXD056039

PXD056039 is an original dataset announced via ProteomeXchange.

Title	Analysis of immunoprecipitates of HA-EZH2 in RPMI8226 cells transfected with an HA-EZH2 plasmid using Coomassie blue staining and mass spectrometry.
Description	The purpose of this project is to identify proteins that interact with EZH2 in the myeloma cell line RPMI8226, which will further allow us to analyze the downstream molecular mechanisms associated with EZH2.
HostingRepository	PRIDE
AnnounceDate	2025-02-27
AnnouncementXML	Submission_2025-02-27_04:00:28.217.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Huan Liu
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2024-09-20 00:23:46	ID requested
⏵ 1	2025-02-27 04:00:29	announced

10.1038/s41467-025-56506-5;

Liu R, Li Z, Chen R, Fang Z, Liu Z, Liu H, EZH2 serves as a viable therapeutic target for myeloma-induced osteolytic bone destruction. Nat Commun, 16(1):1206(2025) [pubmed]

submitter keyword: Human, Myeloma cells, LC/MS/MS, EZH2

Huan Liu
contact affiliation	Cancer Research Center, School of Medicine, Xiamen University, Xiamen, 361102, China.
contact email	huanliu@xmu.edu.cn
lab head
Huan Liu
contact affiliation	School of Medicine, Xiamen University
contact email	huanliu@xmu.edu.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/02/PXD056039

PRIDE project URI

• PRIDE
  1. PXD056039
     1. Label: PRIDE project
     2. Name: Analysis of immunoprecipitates of HA-EZH2 in RPMI8226 cells transfected with an HA-EZH2 plasmid using Coomassie blue staining and mass spectrometry.