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PXD055913

PXD055913 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProfiling postnatal folliculogenesis in ovaries with loss of oocyte SUMOylation
DescriptionSUMOylation plays a critical role in regulating protein function. In the ovary, disrupting expression of the E2 SUMO conjugation enzyme in mouse oocytes beginning at the primordial follicle stage results in female sterility and loss of the ovarian reserve in early adulthood. To determine how folliculogenesis is disrupted, we used label-free mass spectrometry to profile day 14 control and Ube2i-Gdf9icre ovaries.
HostingRepositoryPRIDE
AnnounceDate2025-05-07
AnnouncementXMLSubmission_2025-05-07_03:11:52.505.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAntrix Jain
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-09-16 13:29:41ID requested
12025-05-07 03:11:53announced
Publication List
10.1093/biolre/ioaf035;
Liao Z, Steenwinkel TE, Moscoso B, Salas E, Patton BK, Rodriguez A, Malovannaya A, Pangas SA, . Biol Reprod, 112(5):932-941(2025) [pubmed]
Keyword List
submitter keyword: fertility,SUMOylation, follicle, ovary, reproduction
Contact List
Stephanie A. Pangas
contact affiliationPathology, Baylor College of Medicine, Houston, TX 77030
contact emailspangas@bcm.edu
lab head
Antrix Jain
contact affiliationBaylor College of Medicine
contact emailantrixj@bcm.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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