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PXD055884

PXD055884 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleEMP1 preserves hematopoietic stem cell potential under homeostasis and radiation-induced injury by alleviating ER stress
DescriptionTo illustrate EMP1-interacting proteins, we performed co-immunoprecipitation (co-IP) followed by mass spectrometry using HSPCs (Lin-c-Kit+) to characterize protein interactomes of EMP1. Murine HSPCs (Lin-c-Kit+) were infected with retrovirus to force EMP1 overexpression (with HA tag). Then IgG or HA antibodies were used to conducted co-immunoprecipitation (co-IP), followed by and mass spectrometry analysis.
HostingRepositoryPRIDE
AnnounceDate2025-03-13
AnnouncementXMLSubmission_2025-03-13_05:13:45.543.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterZhe Chen
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-09-16 02:11:16ID requested
12025-03-13 05:13:45announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: HSPCs, EMP1
Contact List
Zhe Chen
contact affiliationDepartment of Radiological Medicine, School of Basic Medical Sciences, Chongqing Medical University
contact emailchenzhe925@cqmu.edu.cn
lab head
Zhe Chen
contact affiliationChongqing Medical University
contact emailchenzhe925@cqmu.edu.cn
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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