PXD055790

PXD055790 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Comparative characterization of the seven H3K4 methyltransferase in Arabidopsis thaliana
Description	Methylation of H3 lysine 4 (H3K4me) marks transcribed elements of the eukaryotic genome, and their distribution alters dynamically through developmental stages and environmental change. These dynamic regulations are likely achieved by the combinatorial work of H3K4me writers, which multi-cellular organisms carry multiple copies of. To better understand the chromatin targeting mechanisms of H3K4 methyltransferase in plants, here we comparatively characterized the seven H3K4 methyltransferases (ATX(R)s) in model plants Arabidopsis. This MS dataset, complemented with the ChIP-seq and AlphaScreen, provides a characterization of ATX(R)s protein. This work clarified, in combination with previous results, ATX1-5 (TRX/TRR-type methyltransferase) localizes on loci with specific sets of chromatin modifications and DNA motifs. Notably, ATXR3, the major H3K4me3 methyltransferase in Arabidopsis, was not associated with COMPASS, which suggests H3K4me3 regulation in plants and animals is divergent. Our work provides a foundation for understanding the regulation of H3K4 methyltransferases in plants.
HostingRepository	jPOST
AnnounceDate	2025-09-12
AnnouncementXML	Submission_2025-09-11_08:00:04.442.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Satoyo Oya
SpeciesList	scientific name: Arabidopsis thaliana (Mouse-ear cress); NCBI TaxID: 3702;
ModificationList	S-carboxamidomethyl-L-cysteine; L-methionine sulfoxide; O-phospho-L-serine; O-phospho-L-threonine; O4'-phospho-L-tyrosine
Instrument	Orbitrap Exploris 480

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-09-11 18:02:42	ID requested
⏵ 1	2025-09-11 08:00:04	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: A.thaliana, co-IP MS, H3K4me, ATX, ATXR, SET

submitter keyword: A.thaliana, co-IP MS, H3K4me, ATX, ATXR, SET

Contact List

Tetsuji Kakutani
lab head
Satoyo Oya
contact affiliation	UC Davis
dataset submitter

Full Dataset Link List

jPOST dataset URI
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jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST003362/