PXD055747 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomics analysis on SETD2 deficient intestinal epithelial cells |
| Description | SETD2 is a methyltransferase critical for the integrity of epithelial barrier. However, the role of SETD2 in safeguarding epithelial barrier integrity remains largely unexplored. Here, we performed proteomics analysis on intact intestinal barrier with SETD2 present and compromised intestinal barrier with SETD2 loss. To characterize biological responses triggered by SETD2 deletion in compromised intestinal barrier at the protein level, we conducted global proteomics studies. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-04-06 |
| AnnouncementXML | Submission_2026-04-05_23:43:39.075.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Aiting Wang |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090; |
| ModificationList | iodoacetamide derivatized residue |
| Instrument | Q Exactive HF; ultraflex |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2024-09-09 09:11:28 | ID requested | |
| ⏵ 1 | 2026-04-05 23:43:42 | announced | |
Publication List
| Rao H, Wang A, Xu Y, Feng W, Ma C, Wang Z, Zhang W, Su W, Xiao X, Gao WQ, Ding X, Li L, Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier. Adv Sci (Weinh), 13(16):e08168(2026) [pubmed] |
| 10.1002/advs.202508168; |
Keyword List
| submitter keyword: Proteomics;IP-MS |
Contact List
| Aiting Wang |
|---|
| contact affiliation | shanghai jiaotong university |
| contact email | aiting19891@sjtu.edu.cn |
| lab head | |
| Aiting Wang |
|---|
| contact affiliation | shang hai jiaotong university |
| contact email | aiting19891@sjtu.edu.cn |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD055747 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD055747
- Label: PRIDE project
- Name: Proteomics analysis on SETD2 deficient intestinal epithelial cells
