PXD055744 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Unravelling the Proteomic Landscape of Imipenem Resistance in Pseudomonas aeruginosa: A Comparative Investigation between Clinical and Control Strains |
| Description | The proteomic landscape of Pseudomonas aeruginosa under the influence of Imipenem, a commonly used antibiotic, has been the subject of investigation in this study. Our comparative analysis between the world epidemic clinical strain (6378/09) and the control strain (ATCC 27853)has revealed results highlighting the proteomic changes that occur in response to varying Imipenem concentrations. Utilizing label-free quantification (LFQ) intensity scores, protein-level t-tests, and Gene Ontology (GO) enrichment analysis, we have been able to delve deeper into the molecular mechanisms that underpin Imipenem resistance. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-04-13 |
| AnnouncementXML | Submission_2026-04-13_11:05:36.441.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Animesh Sharma |
| SpeciesList | scientific name: Pseudomonas aeruginosa ATCC 700888; NCBI TaxID: NEWT:1163394; |
| ModificationList | deamidated residue |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2024-09-09 07:13:13 | ID requested | |
| ⏵ 1 | 2026-04-13 11:05:37 | announced | |
Publication List
| Eidsaa M, Sharma A, Janasch M, Kuch A, Skoczy, ń, ska A, Di Bartolomeo F, : a comparative investigation between clinical and control strains. Front Cell Infect Microbiol, 15():1623154(2025) [pubmed] |
| 10.3389/fcimb.2025.1623154; |
Keyword List
| submitter keyword: Antimicrobial Resistance, antibiotic challenge , Pseudomonas aeruginosa, Label-free Quantitative Proteomics , imipenem . |
Contact List
| Francesca Di Bartolomeo |
|---|
| contact affiliation | Department of Biotechnology and Nanomedicine, SINTEF Industry, Trondheim 7034, Norway |
| contact email | francesca.dibartolomeo@sintef.no |
| lab head | |
| Animesh Sharma |
|---|
| contact affiliation | Engineer at NTNU, Norway |
| contact email | sharma.animesh@gmail.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD055744 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD055744
- Label: PRIDE project
- Name: Unravelling the Proteomic Landscape of Imipenem Resistance in Pseudomonas aeruginosa: A Comparative Investigation between Clinical and Control Strains
