PXD055531
PXD055531 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Genome-wide synthetic lethal screen identifies SRM as a target that enhances erdafitinib efficacy in FGFR-mutant bladder cancer |
| Description | We perform LC-MS to identify credential genes mediating erdafitinib resistacne |
| HostingRepository | iProX |
| AnnounceDate | 2024-09-04 |
| AnnouncementXML | Submission_2025-10-31_01:25:55.431.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Yanchao Yu |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-09-03 20:16:33 | ID requested | |
| 1 | 2025-01-01 19:44:47 | announced | |
| ⏵ 2 | 2025-10-31 01:25:57 | announced | 2025-10-31: Add info |
Publication List
| Yu Y, Gao X, Zhao H, Sun J, Wang M, Xiong X, Li J, Huang C, Zhang H, Jiang G, Xiao X, A Genome-Wide Synthetic Lethal Screen Identifies Spermidine Synthase as a Target to Enhance Erdafitinib Efficacy in FGFR-Mutant Bladder Cancer. Cancer Res, 85(12):2288-2301(2025) [pubmed] |
Keyword List
| submitter keyword: Bladder cancer, erdafitinib resistance, polyamine metabolism |
Contact List
| Guosong Jiang | |
|---|---|
| contact affiliation | Huazhong University of Science and Technology |
| contact email | jiangguosongdoc@hotmail.com |
| lab head | |
| Yanchao Yu | |
| contact affiliation | Huazhong University of Science and Technology |
| contact email | vfgvfg1980@icloud.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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