PXD055484

PXD055484 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	QCeltis Case Study 3: Dried Blood Spots QC Dataset
Description	A dataset containing dried blood spots from human blood used as quality control samples to monitor variation, used as technical replicates (TR), digestion replicates (DR) and HeLa samples. Dried blood spots are blood from a finger prick spotted onto Whatman cards and dried. An aliquot of pooled, mixed-gender blood sample (Golden West Biosolutions, LLC., Human Whole Blood Lot# PS1000.104) were spotted on the same Whatman cards and used as DRs. 6 DRs were added to each digestion plate to be digested with the cohort data. During LC-MS acquisition, the 6 DRs are run at the beginning of each batch. In addition, the pooled, mixed-gender blood samples were bulk digested and included as TRs. 2 TRs were run for every acquisition batch, with the goal of assessing LC-MS performance. To further this goal, 2 HeLa samples were also run between every 2 MS batches.
HostingRepository	MassIVE
AnnounceDate	2025-06-23
AnnouncementXML	Submission_2025-06-23_12:35:24.621.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Manasa Vegesna
SpeciesList	scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Exploris 480

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-09-02 13:38:12	ID requested
⏵ 1	2025-06-23 12:35:25	announced

Publication List

Vegesna M, Sundararaman N, Bharadwaj A, Washington K, Pandey R, Haghani A, Chazarin B, Binek A, Fu Q, Cheng S, Herrington D, Van Eyk JE, . J Proteome Res, 24(3):1148-1160(2025) [pubmed]

Vegesna M, Sundararaman N, Bharadwaj A, Washington K, Pandey R, Haghani A, Chazarin B, Binek A, Fu Q, Cheng S, Herrington D, Van Eyk JE, . J Proteome Res, 24(3):1148-1160(2025) [pubmed]

Keyword List

submitter keyword: Quality Control, DIA, Technical Replicates, Digestion Replicates, HeLa, Dried Blood Spots

submitter keyword: Quality Control, DIA, Technical Replicates, Digestion Replicates, HeLa, Dried Blood Spots

Contact List

Jennifer Van Eyk
contact affiliation	Cedars Sinai Medical Center
contact email	jennifer.vaneyk@cshs.org
lab head
Manasa Vegesna
contact affiliation	Cedars-Sinai Medical Center
contact email	manasa.vegesna@cshs.org
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v08/MSV000095745/

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v08/MSV000095745/