PXD055324
PXD055324 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Protein mass spectrum analysis of serum from CKD and NC mice |
Description | As for serum (CKD vs. NC =4 vs. 4), the protein was extracted by homogenate and SDT lysis. We utilized immunoaffinity depletion of serum high-abundance proteins. Next, we did the following steps: SDS-PAGE separation, Filter-aided sample preparation (FASP Digestion), TMT labeling, peptide fractionation with reversed-phase (RP) chromatography and mass spectrometry analysis. Mass Spectrometry analysis included Easy nLC, LC-MS/MS and data analysis. Differentially expressed proteins between two groups were determined using the t test (the threshold values were set as P < 0.05 and 1.5-fold change). |
HostingRepository | iProX |
AnnounceDate | 2024-08-25 |
AnnouncementXML | Submission_2025-03-06_23:27:41.369.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Meiqiu Wang |
SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive Plus |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2024-08-28 20:51:16 | ID requested | |
⏵ 1 | 2025-03-06 23:27:42 | announced |
Publication List
Wang M, You L, He X, Peng Y, Wang R, Zhang Z, Shu J, Zhang P, Sun X, Jia L, Xia Z, Ji C, Gao C, Multiomics Analysis Reveals Therapeutic Targets for Chronic Kidney Disease With Sarcopenia. J Cachexia Sarcopenia Muscle, 16(1):e13696(2025) [pubmed] |
Keyword List
submitter keyword: chronic kidney disease, serum, mice |
Contact List
Chunlin Gao | |
---|---|
contact affiliation | Nanjing University |
contact email | shuangmu34@163.com |
lab head | |
Meiqiu Wang | |
contact affiliation | Nanjing University |
contact email | 1481700382@qq.com |
dataset submitter |
Full Dataset Link List
iProX dataset URI |