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PXD055168

PXD055168 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleLC-MS/MS analysis of LINC01956-binding protein in GBM cells
DescriptionLncRNAs interact with other cellular molecules, such as DNA, RNA and proteins, to regulate various biological processes. In our study, we demonstrated that LINC01956 promoted MGMT mRNA nuclear export and led to TMZ resistance. In order to elucidate the potential molecular mechanism of LINC01956 promoting MGMT mRNA nuclear export, RNA pulldown experiments and quantitative proteomics mass-spectrometry (MS) analysis were performed.
HostingRepositoryPRIDE
AnnounceDate2024-10-28
AnnouncementXMLSubmission_2024-10-28_07:39:45.909.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD055168
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterXinyi Liao
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-08-24 07:48:56ID requested
12024-10-28 07:39:46announced
Publication List
10.6019/PXD055168;
10.1126/SCITRANSLMED.ADO1573;
Keyword List
submitter keyword: temozolomide, GBM cells,LINC01956
Contact List
Jun Li
contact affiliationZhongshan School of Medicine, Sun Yat-sen University
contact emaillijun37@mail.sysu.edu.cn
lab head
Xinyi Liao
contact affiliationSun Yat-sen University
contact emailliaoxy27@mail2.sysu.edu.cn
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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