PXD055000

PXD055000 is an original dataset announced via ProteomeXchange.

Title	Combination of Metabolomics, Lipidomics and Molecular Biology to Investigation of Metabolic Disturbance of Short-Term Administration of Emodin
Description	To comprehensively elucidate the possible mechanism of short-term administration of emodin on the metabolic disturbance in vivo, our study utilized both LC/MS and NMR platforms for untargeted metabolomics studies. These analyses aimed to identify potential biomarkers associated with emodin-induced metabolic disturbances in mice. Subsequently, we delved into lipidomics to explore lipid metabolism systematically and determined the position of C=C double bonds in unsaturated lipids.
HostingRepository	PRIDE
AnnounceDate	2024-10-17
AnnouncementXML	Submission_2024-10-17_05:07:10.442.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Haitao Wang
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q TRAP; Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2024-08-19 06:52:01	ID requested
⏵ 1	2024-10-17 05:07:11	announced

Wang H, Mao R, Wang L, Wang C, Teka T, Zhang Z, Choi SS, Fu Z, Han L, Combination of Metabolomics, Lipidomics, and Molecular Biology for the Investigation of the Metabolic Disturbance of Short-Term Administration of Emodin. J Proteome Res, 23(10):4327-4342(2024) [pubmed]

10.1021/acs.jproteome.4c00313;

submitter keyword: Metabolomics,Mouse, LC-MS, Lipidomics

Lifeng Han
contact affiliation	State Key Laboratory of Component-based Chinese Medicine, Haihe Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, Jinghai, Tianjin 301617, Peoples R China
contact email	hanlifeng@tjutcm.edu.cn
lab head
Haitao Wang
contact affiliation	Tianjin University of Traditional Chinese Medicine
contact email	wang_ht00@163.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/10/PXD055000

PRIDE project URI

• PRIDE
  1. PXD055000
     1. Label: PRIDE project
     2. Name: Combination of Metabolomics, Lipidomics and Molecular Biology to Investigation of Metabolic Disturbance of Short-Term Administration of Emodin