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PXD054941

PXD054941 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMulti-omics reveals changes in astrocyte fatty acid metabolism during early stages of Alzheimer's disease
DescriptionProtein from astrocytes of 6-month-old AD and WT mice (n=3) was extracted and digested using the iST kit (PreOmics) following the manufacturer's protocol. For label-free LC-MS analysis, samples were loaded onto a 25 cm C18 analytical column (Ionopticks) at a flow rate of 300 nL/min and subjected to gradient elution using solvents A (H2O-FA, 99.9:0.1 v/v) and B (ACN-FA, 99.9:0.1 v/v).For the database search conducted using MaxQuant, utilizing the Andromeda search engine for label-free quantification (LFQ) analysis.
HostingRepositoryiProX
AnnounceDate2024-08-16
AnnouncementXMLSubmission_2024-08-15_20:20:34.566.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJie Zhong
SpeciesList scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-08-15 20:20:09ID requested
12024-08-15 20:20:34announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: astrocytes AD 6m
Contact List
Jun Wan
contact affiliationShenzhen - Peking University - the Hong Kong University of Science and Technology Medical Center
contact emailwanj@sustech.eud.cn
lab head
Jie Zhong
contact affiliationShenzhen - Peking University - the Hong Kong University of Science and Technology Medical Center
contact email2324530926@qq.com
dataset submitter
Full Dataset Link List
iProX dataset URI