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PXD054775

PXD054775 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic dataset of secretome derived from Placental mesenchymal stem cells
DescriptionThe use of perinatal MSCs remains largely unexplored. Consequently, there is a significant gap in knowledge regarding the optimal selection of perinatal MSCs and their appropriate administration to maximize the benefits for DFU treatment. Moreover, there is a lack of direct comparison among different types of perinatal MSCs. In this study, we aimed to address these gaps by comparing the secretome profiles of MSCs derived from human umbilical cord (UC), chorionic villi (CV), and decidua basalis (DC) of the human placenta. We utilized mass spectrometry to analyze the protein components in the secretome derived from hUCMSCs, hCVMSCs, and hDCMSCs. Over 1000 secreted proteins were quantified by mass spectroscopy in secretome of MSCs, with 435 being commonly expressed.
HostingRepositoryMassIVE
AnnounceDate2025-02-02
AnnouncementXMLSubmission_2025-02-02_18:46:08.536.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterkaka
SpeciesList scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-08-10 05:26:39ID requested
12025-02-02 18:46:08announced
Publication List
no publication
Keyword List
submitter keyword: Mesenchymal stromal cells, Secretome, Placenta, Proteomics
Contact List
Xiaohua Jiang, School of Biomedical Sciences, Faculty of Medicine
contact affiliationThe Chinese University of Hong Kong
contact emailxjiang@cuhk.edu.hk
lab head
kaka
contact affiliationThe chinese university of Hong Kong
contact emailjiaweihuang@link.cuhk.edu.hk
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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