PXD054616

PXD054616 is an original dataset announced via ProteomeXchange.

Title	Using proximity labeling by turboID (biotin ligase) fused with PAICS combined with LC-MS for identification of the acetyltransferase associated with PAICS in oncogene RAS activation induced senescent human IMR90 cell
Description	We performed proximity labeling by turboID combined with LC-MS and identified PCAF which interacts with PAICS. Moreover, PCAF promotes the acetylation of PAICS and decreases the protein stability of PAICS. Here, we identify the specific acetyltransferase PCAF that may be involved in the acetylation modification of PAICS using LC-MS.
HostingRepository	PRIDE
AnnounceDate	2025-02-13
AnnouncementXML	Submission_2025-02-12_17:48:29.890.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yang Li
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2024-08-05 20:55:39	ID requested
⏵ 1	2025-02-12 17:48:30	announced

Dataset with its publication pending

submitter keyword: Human, IMR90, LC-MS

Pingyu Liu
contact affiliation	Human Phenome Institute,Zhangjiang Fudan International Innovation Center, Fudan University, Shanghai, China
contact email	pingyu_liu@fudan.edu.cn
lab head
Yang Li
contact affiliation	fudan university
contact email	yangleduo1998@163.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/02/PXD054616

PRIDE project URI

• PRIDE
  1. PXD054616
     1. Label: PRIDE project
     2. Name: Using proximity labeling by turboID (biotin ligase) fused with PAICS combined with LC-MS for identification of the acetyltransferase associated with PAICS in oncogene RAS activation induced senescent human IMR90 cell