PXD054616 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Using proximity labeling by turboID (biotin ligase) fused with PAICS combined with LC-MS for identification of the acetyltransferase associated with PAICS in oncogene RAS activation induced senescent human IMR90 cell |
Description | We performed proximity labeling by turboID combined with LC-MS and identified PCAF which interacts with PAICS. Moreover, PCAF promotes the acetylation of PAICS and decreases the protein stability of PAICS. Here, we identify the specific acetyltransferase PCAF that may be involved in the acetylation modification of PAICS using LC-MS. |
HostingRepository | PRIDE |
AnnounceDate | 2025-02-13 |
AnnouncementXML | Submission_2025-02-12_17:48:29.890.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Yang Li |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-08-05 20:55:39 | ID requested | |
⏵ 1 | 2025-02-12 17:48:30 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Human, IMR90, LC-MS |
Contact List
Pingyu Liu |
contact affiliation | Human Phenome Institute,Zhangjiang Fudan International Innovation Center, Fudan University, Shanghai, China |
contact email | pingyu_liu@fudan.edu.cn |
lab head | |
Yang Li |
contact affiliation | fudan university |
contact email | yangleduo1998@163.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/02/PXD054616 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD054616
- Label: PRIDE project
- Name: Using proximity labeling by turboID (biotin ligase) fused with PAICS combined with LC-MS for identification of the acetyltransferase associated with PAICS in oncogene RAS activation induced senescent human IMR90 cell