PXD054569
PXD054569 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Analysis of blood protein markers for early detection and diagnosis of advanced adenomatous and colorectal cancer |
Description | This study constructed a CRC early screening model using blood proteomics, achieving high accuracy and sensitivity in detecting early CRC and AA. We explored colorectal cancer (CRC)-related protein biomarkers by proteome-wide differential expression analysis based on a case-control design. The blood samples form 150 colorectal cancer (CRC) cases and 50 controls were collected. The blood samples from 50 individuals with advanced adenoma were also collected and analyzed in another subproject study. Plasma protein measurements were generated using the iodo Tandem Mass Tags (TMT)-6plex quantitative proteomics. Plasma proteomics data from all samples (150 CRC cases, 50 individuals with advanced adenoma, and 50 controls) were submitted. |
HostingRepository | iProX |
AnnounceDate | 2024-08-03 |
AnnouncementXML | Submission_2024-08-05_00:27:20.188.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Jingsun Wei |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive HF-X |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2024-08-05 00:26:48 | ID requested | |
⏵ 1 | 2024-08-05 00:27:20 | announced |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: early detection, colorectal cancer |
Contact List
Qian Xiao | |
---|---|
contact affiliation | The Second Affiliated Hospital, Zhejiang University School of Medicine |
contact email | qxiao3@zju.edu.cn |
lab head | |
Jingsun Wei | |
contact affiliation | The Second Affiliated Hospital, Zhejiang University School of Medicine |
contact email | jingsunwei@zju.edu.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |