PXD054498 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Multiple classes of antigen contribute to the antigenic landscape of mesothelioma |
Description | Mesothelioma is an incurable, asbestos-exposure related cancer that typically affects the lining or pleura of the lungs. Symptoms typically develop many decades after initial exposure to asbestos, leaving an enduring legacy of disease. Vaccine-induced augmentation of immune responses unleashed during checkpoint blockade may provide further clinical benefit in mesothelioma. In this study we explore the HLA class I antigenic landscape (or immunopeptidome) of mesothelioma in patient derived cell line and clinical material (pleural effusion samples). |
HostingRepository | PRIDE |
AnnounceDate | 2025-05-07 |
AnnouncementXML | Submission_2025-05-06_23:05:21.852.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD054498 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Kirti Pandey |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | phosphorylated residue; monohydroxylated residue; L-cysteine amide; deamidated residue |
Instrument | Bruker Daltonics timsTOF series |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-08-01 07:30:53 | ID requested | |
⏵ 1 | 2025-05-06 23:05:22 | announced | |
Publication List
10.1016/j.mcpro.2025.100925; |
10.6019/PXD054498; |
Pandey K, Faridi P, Ayala R, Lee YCG, Rouse E, Krishna SSG, Dick I, Redwood A, Robinson B, Creaney J, Purcell AW, Multiple Classes of Antigen Contribute to the Antigenic Landscape of Mesothelioma. Mol Cell Proteomics, 24(3):100925(2025) [pubmed] |
Keyword List
submitter keyword: mass spectrometry,HLA class I, Mesothelioma, asbestos related cancer, Immunopeptidomics, lung cancer |
Contact List
Anthony Wayne |
contact affiliation | Department of Biochemistry and Molecular Biology and Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Melbourne, Victoria, Australia |
contact email | anthony.purcell@monash.edu |
lab head | |
Kirti Pandey |
contact affiliation | Monash University |
contact email | kirti.pandey1@monash.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD054498 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD054498
- Label: PRIDE project
- Name: Multiple classes of antigen contribute to the antigenic landscape of mesothelioma