PXD054404

PXD054404 is an original dataset announced via ProteomeXchange.

Title	A multi-omics study of epigenetic changes in type II alveolar cells in A/J mice exposed to lipopolysaccharide and environmental tobacco smoke
Description	A/J mice were exposed to environmental tobacco smoke, lipopolysaccharide, or clean air over the course of several weeks. Following exposure, subjects were sacrificed and their type II pneumocytes were isolated for multi-omic analyses.
HostingRepository	PRIDE
AnnounceDate	2025-05-07
AnnouncementXML	Submission_2025-05-06_23:18:10.388.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Andrew Rajczewski
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2024-07-30 10:24:45	ID requested
⏵ 1	2025-05-06 23:18:11	announced

10.3390/ijms25179365;

Han Q, Fernandez J, Rajczewski AT, Kono TJY, Weirath NA, Rahim A, Lee AS, Seabloom D, Tretyakova NY, A Multi-Omics Study of Epigenetic Changes in Type II Alveolar Cells of A/J Mice Exposed to Environmental Tobacco Smoke. Int J Mol Sci, 25(17):(2024) [pubmed]

submitter keyword: lung cancer, multi-omics, tobacco smoke

Natalia Tretyakova
contact affiliation	Department of Medicinal Chemistry, University of Minnesota
contact email	trety001@umn.edu
lab head
Andrew Rajczewski
contact affiliation	University of Minnesota
contact email	rajcz001@umn.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD054404

PRIDE project URI

• PRIDE
  1. PXD054404
     1. Label: PRIDE project
     2. Name: A multi-omics study of epigenetic changes in type II alveolar cells in A/J mice exposed to lipopolysaccharide and environmental tobacco smoke