PXD054330

PXD054330 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomic profiling of human corneal epithelial cells under hyperosmotic stress
Description	This project compared the proteomic change between human corneal epithelial cells cultured under hyperosmotic and isosmotic condition. This aimed to reveal differentially expressed proteins that was associated with osmoregulation in human corneal epithelial cells.
HostingRepository	jPOST
AnnounceDate	2025-05-14
AnnouncementXML	Submission_2025-05-23_04:31:44.722.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kenrick Kai-yuen CHAN
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	S-carboxamidomethyl-L-cysteine; L-methionine sulfoxide; alpha-amino acetylated residue
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-07-29 01:03:22	ID requested
1	2025-05-13 20:59:43	announced
⏵ 2	2025-05-23 04:31:45	announced	2025-05-23: Updated PubMed.

Publication List

Chan KK, Lee AC, Chung SR, Wong MS, Do CW, Lam TC, Kong HK, Upregulations of SNAT2 and GLS-1 Are Key Osmoregulatory Responses of Human Corneal Epithelial Cells to Hyperosmotic Stress. J Proteome Res, 24(6):2771-2782(2025) [pubmed]

Chan KK, Lee AC, Chung SR, Wong MS, Do CW, Lam TC, Kong HK, Upregulations of SNAT2 and GLS-1 Are Key Osmoregulatory Responses of Human Corneal Epithelial Cells to Hyperosmotic Stress. J Proteome Res, 24(6):2771-2782(2025) [pubmed]

Keyword List

submitter keyword: Human, cornea, epithelia, hyperosmolarity, dry eye disease

submitter keyword: Human, cornea, epithelia, hyperosmolarity, dry eye disease

Contact List

Hang-kin KONG
lab head
Kenrick Kai-yuen CHAN
contact affiliation	Centre for Eye and Vision Research
dataset submitter

Full Dataset Link List

jPOST dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST003233/

jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST003233/