PXD054166
PXD054166 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | P. micra surface protein TmpC interacts directly with OSCC cell lines via CKAP4 |
| Description | P. micra surface protein TmpC interacts directly with OSCC cell lines via CKAP4, a receptor frequently overexpressed in human OSCC tumors. The interaction of TmpC and CKAP4 mediates bacterial attachment, invasion, and metastasis-promoting effects of P. micra on OSCC and subsequently activates HIF-1α and autophagy signaling, via CKAP4-RanBP2 and CKAP4-NBR1 interaction, respectively. |
| HostingRepository | iProX |
| AnnounceDate | 2024-07-24 |
| AnnouncementXML | Submission_2025-12-04_23:37:34.126.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Houbao Qi |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | LTQ Orbitrap Elite |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-07-23 23:08:04 | ID requested | |
| 1 | 2024-07-23 23:09:15 | announced | |
| ⏵ 2 | 2025-12-04 23:37:35 | announced | 2025-12-05: Add info. |
Publication List
| Qi H, Gao H, Li M, Sun T, Gu X, Wei L, Zhi M, Li Z, Fu D, Liu Y, Wei Z, Dou Y, Feng Q, Parvimonas micra promotes oral squamous cell carcinoma metastasis through TmpC-CKAP4 axis. Nat Commun, 16(1):2305(2025) [pubmed] |
Keyword List
| submitter keyword: Tmpc, CKAP4, OSCC |
Contact List
| Qiang Feng | |
|---|---|
| contact affiliation | Shandong University |
| contact email | fengqiang@sdu.edu.cn |
| lab head | |
| Houbao Qi | |
| contact affiliation | Shandong University |
| contact email | byqihoubao@126.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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