PXD054136

PXD054136 is an original dataset announced via ProteomeXchange.

Title	Identification of conjugation site of T-DM1
Description	Ado-trastuzumab emtansine(T-DM1) is manufactured by conjugating DM1 to lysine of Trastuzumab via a non-cleavable linker in a non-specific mode.conjugated site of T-DM1 were identified using a bottom-up strategy through LC-HR-MS/MS.
HostingRepository	PRIDE
AnnounceDate	2025-03-05
AnnouncementXML	Submission_2025-03-04_23:16:51.834.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Meiling Qi
SpeciesList	scientific name: Homo sapiens environmental sample; NCBI TaxID: 2665953;
ModificationList	monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2024-07-23 02:49:54	ID requested
⏵ 1	2025-03-04 23:16:52	announced

10.1021/ACS.JPROTEOME.4C00631;

submitter keyword: conjugation site,LC-MS/MS

Hongliang Jiang
contact affiliation	Tongji School of Pharmacy, Huazhong University of Science and Technology
contact email	jianghongliang@hust.edu.cn
lab head
Meiling Qi
contact affiliation	Tongji School of Pharmacy, Huazhong University of Science and Technology
contact email	qimeiling0930@163.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/03/PXD054136

PRIDE project URI

• PRIDE
  1. PXD054136
     1. Label: PRIDE project
     2. Name: Identification of conjugation site of T-DM1