PXD054091

PXD054091 is an original dataset announced via ProteomeXchange.

Title	Proteomic Analysis of the Capability to Enrich Rat Nucleus Pulposus Cell Membrane Proteins on Different Glucomannan Esters
Description	Nucleus pulposus cells show unique phenotypes and morphology on different glucomannan esters. Various protein receptors on the membrane surface are involved in cell adhesion, morphology maintenance and phenotype regulation. In this project, the cell membrane proteins of the nucleus pulposus cells were extracted and purified and incubated with different glucomannan esters to detect differentially enriched proteins to comprehensively evaluate the specific mechanism by which glucomannan esters regulate cell function.
HostingRepository	iProX
AnnounceDate	2024-07-20
AnnouncementXML	Submission_2025-12-04_23:39:12.454.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yu Liu
SpeciesList	scientific name: Rattus norvegicus; NCBI TaxID: 10116;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2024-07-22 00:07:43	ID requested
1	2025-12-04 23:38:43	announced
⏵ 2	2025-12-04 23:39:13	announced	2025-12-05: Add info.

Liu Y, Chao T, Li Y, Peng P, Ge G, Geng D, Dong L, Wang C, An enzyme-proof glycan glue for extracellular matrix to ameliorate intervertebral disc degeneration. Nat Commun, 16(1):3629(2025) [pubmed]

submitter keyword: Nucleus pulposus cells

Membrane proteins

Glucomannan esters

Chunming Wang
contact affiliation	State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences of University of Macau
contact email	cmwang@um.edu.mo
lab head
Yu Liu
contact affiliation	State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences of University of Macau
contact email	yc17533@um.edu.mo
dataset submitter

iProX dataset URI