PXD054069 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | LC/MS Analysis of Phosphorylated Protein Changes in Mouse Brain Tissue After LPS Treatment and Angong Niuhuang Wan Administration |
Description | Introduction: Angong Niuhuang Wan (AGNHW), developed in the Qing dynasty (18th century) for treating consciousness disturbances caused by severe infections, has already been used to treat brain edema caused by ischemia-reperfusion. However, it remains unclear whether AGNHW can ameliorate vascular-origin brain edema caused by lipopolysaccharides (LPS).This study explores the ameliorative effects of AGNHW on cerebrovascular edema in mice caused by LPS, as well as its potential mechanisms.Mice were divided into four groups: Control, LPS 26 h, LPS 48 h, and LPS + AGNHW_M. Enriched phosphorylated peptides were extracted from mouse brain tissues at the corresponding time points and subjected to phosphoproteomic analysis. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_06:51:24.141.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | BoTong Liu |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | phosphorylated residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-07-19 10:21:18 | ID requested | |
1 | 2024-07-25 09:50:56 | announced | |
⏵ 2 | 2024-10-22 06:51:24 | announced | 2024-10-22: Updated project metadata. |
Publication List
Keyword List
submitter keyword: LC/MS,AGNHW,Phosphoproteome |
Contact List
Jing-Yan Han |
contact affiliation | Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University |
contact email | hanjingyan@bjmu.edu.cn |
lab head | |
BoTong Liu |
contact affiliation | Peking university |
contact email | liubotong@163.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD054069
- Label: PRIDE project
- Name: LC/MS Analysis of Phosphorylated Protein Changes in Mouse Brain Tissue After LPS Treatment and Angong Niuhuang Wan Administration