PXD053997
PXD053997 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Anti-Toxoplasma gondii effect of vorinostat in vitro and in vivo |
Description | Toxoplasma gondii is an important pathogenic protozoon that infects up to one-third of the world's population. In immunocompetent individuals, the infection generally is asymptomatic. However, in immunocompromised patients, the infection can lead to severe and fatal complications. This is due to the conversion of bradyzoites to tachyzoites as a result of reduced immune pressure. Therefore, it is necessary to discover drugs that have anti-Toxoplasma effect while simultaneously being effective against cancer.Our findings suggest that vorinostat demonstrates potency against T. gondii both in vitro and in vivo, which offers promise for treatment of human toxoplasmosis in cancer patients. |
HostingRepository | iProX |
AnnounceDate | 2024-07-17 |
AnnouncementXML | Submission_2024-07-17_00:34:37.379.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Chunxue Zhou |
SpeciesList | scientific name: Toxoplasma gondii RH-88; NCBI TaxID: 1208370; |
ModificationList | No PTMs are included in the dataset |
Instrument | Orbitrap Astral |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2024-07-17 00:32:23 | ID requested | |
⏵ 1 | 2024-07-17 00:34:37 | announced |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Toxoplasma gondii |
Contact List
Chunxue Zhou | |
---|---|
contact affiliation | Shandong University |
contact email | zhouchunxue23@163.com |
lab head | |
Chunxue Zhou | |
contact affiliation | Shandong University |
contact email | zhouchunxue23@163.com |
dataset submitter |
Full Dataset Link List
iProX dataset URI |