PXD053919

PXD053919 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	N1-Methylpseudouridine and pseudouridine modifications modulate mRNA decoding during translation
Description	Mass spectrometry on affinity-purified luciferase produced from constitutively modified or unmodified mRNA in HEK293 cells.
HostingRepository	PRIDE
AnnounceDate	2025-05-07
AnnouncementXML	Submission_2025-05-06_21:32:13.868.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD053919
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Daniel Eyler
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-07-12 09:37:40	ID requested
⏵ 1	2025-05-06 21:32:14	announced

Publication List

10.1038/s41467-024-51301-0;
Monroe J, Eyler DE, Mitchell L, Deb I, Bojanowski A, Srinivas P, Dunham CM, Roy B, Frank AT, Koutmou KS, N1-Methylpseudouridine and pseudouridine modifications modulate mRNA decoding during translation. Nat Commun, 15(1):8119(2024) [pubmed]
10.6019/PXD053919;

10.1038/s41467-024-51301-0;

Monroe J, Eyler DE, Mitchell L, Deb I, Bojanowski A, Srinivas P, Dunham CM, Roy B, Frank AT, Koutmou KS, N1-Methylpseudouridine and pseudouridine modifications modulate mRNA decoding during translation. Nat Commun, 15(1):8119(2024) [pubmed]

10.6019/PXD053919;

Keyword List

submitter keyword: N1-methylpseudouridine, ribosome,translation

submitter keyword: N1-methylpseudouridine, ribosome,translation

Contact List

Kristin Koutmou
contact affiliation	University of Michigan Department of Chemistry 930 N. University Ave. Ann Arbor MI 48109
contact email	kkoutmou@umich.edu
lab head
Daniel Eyler
contact affiliation	University of Michigan
contact email	deyler@umich.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD053919
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD053919

PRIDE project URI

Repository Record List

[ + ]