PXD053812

PXD053812 is an original dataset announced via ProteomeXchange.

Title	Multi-center study of E.coli colonies as a proof of concept for federated proteomics.
Description	Quantitative mass spectrometry has transformed proteomics by allowing the simultaneous quantification of thousands of proteins. To boost statistical power, it is necessary to increase sample sizes by combining patient-derived data from various institutions. However, this practice raises significant privacy concerns. We created a DIA-LFQ dataset containing 118 samples generated from Escherichia coli MG1655 (DSM 18039) cultures and distributed them to five independent proteomics centers. This distributed data were used as a proof of concept to introduce FedProt - the first privacy-preserving tool for collaborative differential protein abundance analysis of distributed data.
HostingRepository	PRIDE
AnnounceDate	2025-04-29
AnnouncementXML	Submission_2025-04-29_08:32:20.708.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yuliya Burankova
SpeciesList	scientific name: Escherichia coli; NCBI TaxID: 562;
ModificationList	acetylated residue
Instrument	timsTOF Pro; Orbitrap Fusion Lumos; Orbitrap Exploris 480; Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2024-07-09 17:19:30	ID requested
⏵ 1	2025-04-29 08:32:21	announced

10.48550/ARXIV.2407.15220;

submitter keyword: E.coli, DIA-LFQ

Prof. Dr. Jan Baumbach
contact affiliation	Institute for Computational Systems Biology, University of Hamburg, Hamburg, Germany
contact email	jan.baumbach@uni-hamburg.de
lab head
Yuliya Burankova
contact affiliation	Technical University of Munich, University of Hamburg
contact email	yuliya.burankova@uni-hamburg.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/04/PXD053812

PRIDE project URI

• PRIDE
  1. PXD053812
     1. Label: PRIDE project
     2. Name: Multi-center study of E.coli colonies as a proof of concept for federated proteomics.