PXD053812 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Multi-center study of E.coli colonies as a proof of concept for federated proteomics. |
Description | Quantitative mass spectrometry has transformed proteomics by allowing the simultaneous quantification of thousands of proteins. To boost statistical power, it is necessary to increase sample sizes by combining patient-derived data from various institutions. However, this practice raises significant privacy concerns. We created a DIA-LFQ dataset containing 118 samples generated from Escherichia coli MG1655 (DSM 18039) cultures and distributed them to five independent proteomics centers. This distributed data were used as a proof of concept to introduce FedProt - the first privacy-preserving tool for collaborative differential protein abundance analysis of distributed data. |
HostingRepository | PRIDE |
AnnounceDate | 2025-04-29 |
AnnouncementXML | Submission_2025-04-29_08:32:20.708.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Yuliya Burankova |
SpeciesList | scientific name: Escherichia coli; NCBI TaxID: 562; |
ModificationList | acetylated residue |
Instrument | timsTOF Pro; Orbitrap Fusion Lumos; Orbitrap Exploris 480; Q Exactive HF-X |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-07-09 17:19:30 | ID requested | |
⏵ 1 | 2025-04-29 08:32:21 | announced | |
Publication List
Keyword List
submitter keyword: E.coli, DIA-LFQ |
Contact List
Prof. Dr. Jan Baumbach |
contact affiliation | Institute for Computational Systems Biology, University of Hamburg, Hamburg, Germany |
contact email | jan.baumbach@uni-hamburg.de |
lab head | |
Yuliya Burankova |
contact affiliation | Technical University of Munich, University of Hamburg |
contact email | yuliya.burankova@uni-hamburg.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/04/PXD053812 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD053812
- Label: PRIDE project
- Name: Multi-center study of E.coli colonies as a proof of concept for federated proteomics.