PXD053798

PXD053798 is an original dataset announced via ProteomeXchange.

Title	The proteomic content of Varroa destructor gut varies according to the developmental stage of its host
Description	Varroa destructor is one of the major parasitic pests in modern beekeeping worldwide. Since it shifted host from Asian to Western honey bees, it was shown to weaken colonies by feeding on both immature and adult stages while transmitting several deadly viruses in the process. Nutrition, an overlooked aspect of parasite biology, is thus a key to comprehend the V. destructor life cycle and its impacts on its honey bee host. We explored the feeding physiology of this ectoparasite both through artificial feeding and by dissecting their gut and analysing their protein content especially in terms of host-derived nutrients. We found that the mite requires higher quantities of carbohydrates than proteins and that the nature of these proteins is crucial for its survival. The abundance of these essential nutrients such as Vitellogenin or Hexamerin varies throughout the bee development and could directly impact the parasite physiology. The analysis and identification of key proteins required for the mite’s survival and reproduction will pave the way for the development of more specific control strategies.
HostingRepository	PRIDE
AnnounceDate	2024-12-16
AnnouncementXML	Submission_2024-12-16_06:16:00.272.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD053798
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Karim Arafah
SpeciesList	scientific name: Apis mellifera (Honeybee); NCBI TaxID: 7460; scientific name: Varroa destructor; NCBI TaxID: 109461;
ModificationList	S-pyridylethyl-L-cysteine; acetylated residue; monohydroxylated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2024-07-09 07:04:54	ID requested
⏵ 1	2024-12-16 06:16:00	announced

10.6019/PXD053798;

10.1371/JOURNAL.PPAT.1012802;

submitter keyword: proteomics, haemolymph, label free quantification,Varroa destructor, fat bodies, honey bees

Karim ARAFAH
contact affiliation	Plateforme BioPark Archamps
contact email	karim.arafah@biopark-archamps.org
lab head
Karim Arafah
contact affiliation	Biopark Archamps
contact email	karim.arafah@biopark-archamps.org
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/12/PXD053798

PRIDE project URI

• PRIDE
  1. PXD053798
     1. Label: PRIDE project
     2. Name: The proteomic content of Varroa destructor gut varies according to the developmental stage of its host