PXD053746

PXD053746 is an original dataset announced via ProteomeXchange.

Title	In-depth Proteomics and Phosphoproteomics Reveal Biomarkers and Molecular Pathways of Chronic Intermittent Hypoxia in Mice
Description	Obstructive sleep apnea (OSA) syndrome is characterized by Chronic Intermittent Hypoxia (CIH). In this study, we employed Data-independent acquisition (DIA) Mass Spectrometry to conduct comprehensive proteomic and phosphoproteomic profiling of a murine model subjected to Chronic Intermittent Hypoxia (CIH), a model we had previously established. Utilizing three CIH and three normal control genioglossus samples, we gathered valuable insights into the molecular alterations associated with CIH.
HostingRepository	iProX
AnnounceDate	2024-07-08
AnnouncementXML	Submission_2024-12-01_20:18:44.285.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Huanhuan Fang
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	phosphorylated residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2024-07-08 01:58:25	ID requested
⏵ 1	2024-12-01 20:18:45	announced

Fang H, Zhang Y, Zhu L, Lyu J, Li Q, In-depth proteomics and Phosphoproteomics reveal biomarkers and molecular pathways of chronic intermittent hypoxia in mice. J Proteomics, 311():105334(2025) [pubmed]

submitter keyword: Proteome, Phosphoproteome, Chronic Intermittent Hypoxia, Obstructive Sleep Apnea

Qiang Li
contact affiliation	Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University
contact email	lqq401@sina.com
lab head
Huanhuan Fang
contact affiliation	Department of Oral and Maxillofacial Surgery, the First Affiliated Hospital of Wannan Medical College
contact email	fhhgsy@sina.com
dataset submitter

iProX dataset URI