PXD053553

PXD053553 is an original dataset announced via ProteomeXchange.

Title	Exploring changes in ARGs during chromium reduction by Bacillus cereus SH-1 exposed to chromium-contaminated wastewater: a functional analysis from gene to protease
Description	This study researched the combined effects of hexavalent chromium (Cr(VI)) concentration and antibiotics on the ARGs of Bacillus cereus SH-1. As the Cr(VI) concentration increased, it triggered Reactive Oxygen Species (ROS) oxidative stress in SH-1, increased antioxidant enzyme activity, enhanced plasmid conjugative transfer and reduced the removal efficiency of Cr(VI) by SH-1. Meanwhile, antibiotic resistance varied with TET (Tetracycline) and AMC (Amoxicillin) MICs (minimum inhibitory concentration) rising and AZM (Azithromycin) and CL (Chloramphenicol) MICs decreasing with Cr(VI) induction. Overexpression of eight genes of the HAE-1 family efflux pumps was detected through metagenomics and proteomics. Co-contamination of Cr(VI) and antibiotics led to the emergence and spread of antibiotics resistant bacteria (ARBs).
HostingRepository	iProX
AnnounceDate	2024-07-01
AnnouncementXML	Submission_2024-07-01_21:47:28.990.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Hui Wu
SpeciesList	scientific name: Bacillus cereus C1L; NCBI TaxID: 1003239;
ModificationList	No PTMs are included in the dataset
Instrument	MassHunter Easy Access

Revision	Datetime	Status	ChangeLog Entry
0	2024-07-01 21:46:10	ID requested
⏵ 1	2024-07-01 21:47:29	announced

Dataset with its publication pending

submitter keyword: Bacillus cereus SH-1, Chromium Pollution Removal, Antibiotic Resistance, protease

Dongyun Du
contact affiliation	South-Central Minzu University
contact email	1244584578@qq.com
lab head
Hui Wu
contact affiliation	South-Central Minzu University
contact email	1280627787@qq.com
dataset submitter

iProX dataset URI