PXD053458

PXD053458 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomics analysis of Medulloblastoma
Description	Medulloblastoma (MB) is the most common malignant brain tumor in children. It is a neuroectodermal tumor located in the cerebellum. International consensus recognizes four distinct subgroups of MBs including Wingless (WNT), Sonic Hedgehog (SHH), Group 3 (G3), and Group 4 (G4) with distinct molecular characteristics, prognoses, and mortality rates in patients. Here, we have compiled a large MB cohort encompassing 384 primary MB patient samples with methylome (450k/850k arrays), transcriptome (RNA-seq), proteome, phosphoproteome and metabolome.
HostingRepository	PRIDE
AnnounceDate	2025-12-14
AnnouncementXML	Submission_2025-12-13_20:53:02.673.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Vanessa Masson
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Exploris 480; Q Exactive HF-X

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-06-27 04:57:43	ID requested
⏵ 1	2025-12-13 20:53:03	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: proteomics, multi-omics, cerebellum,Medulloblastoma, metabolism., pediatric brain tumor, phosphoproteomics

submitter keyword: proteomics, multi-omics, cerebellum,Medulloblastoma, metabolism., pediatric brain tumor, phosphoproteomics

Contact List

Damarys Loew
contact affiliation	Head of the Curie Institute Mass Spectrometry Platform
contact email	damarys.loew@curie.fr
lab head
Vanessa Masson
contact affiliation	Institut Curie - Centre de Recherche
contact email	vanessa.masson@curie.fr
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD053458
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD053458

PRIDE project URI

Repository Record List

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