PXD053451

PXD053451 is an original dataset announced via ProteomeXchange.

Title	Site-specific N-glycosylation Characterization of Monoclonal Immunoglobulins in Multiple Myeloma
Description	Monoclonal immunoglobulins (M-proteins) produced by clonal plasma cells are the main cause of multiple myeloma (MM), and hypocomplementemia is observed in some patients with MM. Previous studies have suggested that the glycosylation of immunoglobulins is associated with complement-mediated effector activities. However, the site-specific N-glycosylation of monoclonal immunoglobulins in MM and their effects on complement system activation remain unclear.
HostingRepository	iProX
AnnounceDate	2024-06-27
AnnouncementXML	Submission_2024-06-27_00:25:37.778.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yong Zhang
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	deaminated residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2024-06-27 00:24:37	ID requested
⏵ 1	2024-06-27 00:25:38	announced

Dataset with its publication pending

submitter keyword: N-glycosylation, mass spectrometry, monoclonal immunoglobulins, multiple myeloma

Yong Zhang
contact affiliation	West China Hospital, Sichuan University
contact email	nankai1989@foxmail.com
lab head
Yong Zhang
contact affiliation	West China Hospital, Sichuan University
contact email	nankai1989@foxmail.com
dataset submitter

iProX dataset URI