PXD053397

PXD053397 is an original dataset announced via ProteomeXchange.

Title	miR-493-5p, miR-3662, miR-589-3p, human A549 cells, LC-MSMS
Description	miR-493-5p, miR-3662, and miR-589-3p were estimated as working microRNAs in bleomycin- and methotrexate-induced phenotypic changes in A549 cells via microRNAs-Proteins Analysis of Integrative Relationship (miR-PAIR). To verify the effect of these miRNAs on the their target protein expression levels, comprehensive expression of proteins in A549 cells treated with miR-493-59, miR-3662, and miR-589-3p mimic was examined by SWATH-MS method. As expected by a miR-PAIR mehtod, almost target proteins were succesfully regulated by miR-493-5p and miR-589-3p mimics.
HostingRepository	PRIDE
AnnounceDate	2025-07-25
AnnouncementXML	Submission_2025-07-25_08:47:21.742.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Masashi Kawami
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	ZenoTOF 7600

Revision	Datetime	Status	ChangeLog Entry
0	2024-06-25 07:50:39	ID requested
⏵ 1	2025-07-25 08:47:22	announced

10.1016/J.BBAGEN.2024.130746;

submitter keyword: Human, LC-MSMS, microRNAs, Lung, methotrexate, bleomycin

Yasuo Uchida
contact affiliation	Department of Molecular Systems Pharmaceutics, Graduate School of Biomedical and Health Sciences, Hiroshima University
contact email	yuchida@hiroshima-u.ac.jp
lab head
Masashi Kawami
contact affiliation	Mukogawa Women's University
contact email	kawami_masashi_x@mukogawa-u.ac.jp
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/07/PXD053397

PRIDE project URI

• PRIDE
  1. PXD053397
     1. Label: PRIDE project
     2. Name: miR-493-5p, miR-3662, miR-589-3p, human A549 cells, LC-MSMS