PXD053305 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | The Tel1 Phosphoproteomic Network |
Description | Large-scale unbiased phosphoproteomics analysis of Tel1-deleted yeast reveal dozens of novel Tel1-dependent phosphorylation events. The canonical S/T-Q motif is enriched amongst these Tel1-dependent sites, but a novel D/E-S/T motif is even more highly enriched. Phosphoproteomics of possible downstream acidophilic kinases Dun1, Rad53, and Hrr25 are performed to determine if these sites may be indirectly Tel1-dependent, but the D/E-S/T sites are not dependent on any of them. |
HostingRepository | PRIDE |
AnnounceDate | 2025-05-07 |
AnnouncementXML | Submission_2025-05-06_21:39:49.420.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | William Comstock |
SpeciesList | scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932; |
ModificationList | 6x(13)C; 6x(13)C; phosphorylated residue |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-06-22 10:59:08 | ID requested | |
⏵ 1 | 2025-05-06 21:39:50 | announced | |
Publication List
Comstock WJ, Bhattarai S, Sanford EJ, Navarro MVAS, Smolka MB, Profiling Tel1 signaling reveals a non-canonical motif targeting DNA repair and telomere control machineries. J Biol Chem, 301(3):108194(2025) [pubmed] |
10.1016/j.jbc.2025.108194; |
Keyword List
submitter keyword: Tel1 Phosphoproteomics Phosphorylation DNA damage signaling network genome maintenance |
Contact List
Marcus Smolka |
contact affiliation | Cornell University |
contact email | mbs266@cornell.edu |
lab head | |
William Comstock |
contact affiliation | Cornell University |
contact email | wc622@cornell.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD053305 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD053305
- Label: PRIDE project
- Name: The Tel1 Phosphoproteomic Network