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PXD053287

PXD053287 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe Detection of Heat Stress by Assessing individual Body Responses to Heat (Heat Strain) in Young and Healthy Non-athlete Participants
DescriptionHeat stress can reduce work performance and increases the risk for work related injuries. An in-depth understanding of the molecular heat strain signature in sweat for an extended personalized molecular monitoring is lacking. The HEATSTAR project is, to the best of our knowledge, the first project to use a personalized study setting to assess the molecular signature of proteomics and metabolomics in sweat during moderate heat stress. It was investigated if biomarker candidates can be identified that allow us to differentiate between various heat stressors. For this, we conducted a personalized, cross-sectional, crossover pilot trial with randomized study visits. Healthy non-athlete participants aged 18-40 were included and four different types of heat stressors applied. The local sweat rate through technical absorbents, the whole body sweat rate, and sweat’s metabolomic as well as proteomic molecular composition were assessed.
HostingRepositoryPRIDE
AnnounceDate2025-04-04
AnnouncementXMLSubmission_2025-04-04_12:10:16.390.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterNoé Brasier
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-06-21 13:09:06ID requested
12025-04-04 12:10:16announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: HEATSTAR,heat stress, sweat,proteomic and metabolommic signature, timsTOF Pro
Contact List
Noé Brasier
contact affiliationInstitute of Translational Medicine, Department Health Science and Technology, ETH Zurich, Zurich, Switzerland
contact emailnbrasier@ethz.ch
lab head
Noé Brasier
contact affiliationETH Zurich
contact emailnbrasier@ethz.ch
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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