PXD053187

PXD053187 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	comparative total proteome analysis for nash biomarker
Description	Nonalcoholic fatty liver disease (NAFLD) is a hepatic condition characterized by excessive fat accumulation, leading to liver fibrosis, cirrhosis, and cancer. Currently, invasive liver biopsy is the only method for identifying and classifying NASH. Mass spectrometry-based proteomics can detect crucial proteins and pathways involved in NASH development. A study using liver and serum samples from mice and humans found altered proteins involved in detoxification, fibrosis, inflammation, and fatty acid metabolism. These findings provide insights into NASH molecular mechanisms and potential diagnostic biomarkers for early diagnosis.
HostingRepository	PRIDE
AnnounceDate	2025-05-07
AnnouncementXML	Submission_2025-05-06_19:33:27.766.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD053187
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Eda ATES
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	carbamoylated residue; acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Eclipse

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-06-17 21:20:46	ID requested
⏵ 1	2025-05-06 19:33:28	announced

Publication List

10.1016/j.mcpro.2025.100921;
Ates E, My Ong HT, Yu SM, Kim JH, Kang MJ, Comparative Analysis of the Total Proteome in Nonalcoholic Steatohepatitis: Identification of Potential Biomarkers. Mol Cell Proteomics, 24(3):100921(2025) [pubmed]
10.6019/PXD053187;

10.1016/j.mcpro.2025.100921;

Ates E, My Ong HT, Yu SM, Kim JH, Kang MJ, Comparative Analysis of the Total Proteome in Nonalcoholic Steatohepatitis: Identification of Potential Biomarkers. Mol Cell Proteomics, 24(3):100921(2025) [pubmed]

10.6019/PXD053187;

Keyword List

submitter keyword: full scan mouse liver tribrid

submitter keyword: full scan mouse liver tribrid

Contact List

Min-Jung Kang
contact affiliation	Korea Institute of Science and Technology
contact email	mjkang1@kist.re.kr
lab head
Eda ATES
contact affiliation	Korea Institute of Science and Technology and KIST School, University of Science and Technology
contact email	eda.ates@kist.re.kr
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD053187
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD053187

PRIDE project URI

Repository Record List

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