PXD053187 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | comparative total proteome analysis for nash biomarker |
Description | Nonalcoholic fatty liver disease (NAFLD) is a hepatic condition characterized by excessive fat accumulation, leading to liver fibrosis, cirrhosis, and cancer. Currently, invasive liver biopsy is the only method for identifying and classifying NASH. Mass spectrometry-based proteomics can detect crucial proteins and pathways involved in NASH development. A study using liver and serum samples from mice and humans found altered proteins involved in detoxification, fibrosis, inflammation, and fatty acid metabolism. These findings provide insights into NASH molecular mechanisms and potential diagnostic biomarkers for early diagnosis. |
HostingRepository | PRIDE |
AnnounceDate | 2025-05-07 |
AnnouncementXML | Submission_2025-05-06_19:33:27.766.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD053187 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Eda ATES |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | carbamoylated residue; acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Eclipse |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-06-17 21:20:46 | ID requested | |
⏵ 1 | 2025-05-06 19:33:28 | announced | |
Publication List
10.1016/j.mcpro.2025.100921; |
Ates E, My Ong HT, Yu SM, Kim JH, Kang MJ, Comparative Analysis of the Total Proteome in Nonalcoholic Steatohepatitis: Identification of Potential Biomarkers. Mol Cell Proteomics, 24(3):100921(2025) [pubmed] |
10.6019/PXD053187; |
Keyword List
submitter keyword: full scan mouse liver tribrid |
Contact List
Min-Jung Kang |
contact affiliation | Korea Institute of Science and Technology |
contact email | mjkang1@kist.re.kr |
lab head | |
Eda ATES |
contact affiliation | Korea Institute of Science and Technology and KIST School, University of Science and Technology |
contact email | eda.ates@kist.re.kr |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD053187 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD053187
- Label: PRIDE project
- Name: comparative total proteome analysis for nash biomarker