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PXD053127

PXD053127 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleFlap endonuclease 1 repairs DNA-protein crosslinks via ADP-ribosylation
DescriptionThe protein composition of DNA-protein crosslinks (DPCs) induced by formaldehyde treatment of human cell lines was analyzed by mass spectrometry.
HostingRepositoryMassIVE
AnnounceDate2025-03-14
AnnouncementXMLSubmission_2025-03-14_12:29:44.057.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterLisa Jenkins
SpeciesList scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationListCarbamidomethyl; Oxidation
InstrumentOrbitrap Fusion; Orbitrap Fusion Lumos; Orbitrap Exploris 480
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-06-14 09:00:24ID requested
12025-03-14 12:29:44announced
Publication List
Sun Y, Jenkins LM, El Touny LH, Zhu L, Yang X, Jo U, Escobedo L, Maity TK, Saha LK, Uribe I, Saha S, Takeda S, Leung AKL, Cheng K, Pommier Y, Flap endonuclease 1 repairs DNA-protein cross-links via ADP-ribosylation-dependent mechanisms. Sci Adv, 11(2):eads2919(2025) [pubmed]
Keyword List
submitter keyword: DNA-protein crosslink, formaldehyde DNA-protein crosslink, In vivo complex of enzyme assay, DPC composition
Contact List
Lisa Jenkins
contact affiliationNCI, NIH
contact emailjenkinsl@mail.nih.gov
lab head
Lisa Jenkins
contact affiliationNCI
contact emailjenkinsl@mail.nih.gov
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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