PXD053127

PXD053127 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Flap endonuclease 1 repairs DNA-protein crosslinks via ADP-ribosylation
Description	The protein composition of DNA-protein crosslinks (DPCs) induced by formaldehyde treatment of human cell lines was analyzed by mass spectrometry.
HostingRepository	MassIVE
AnnounceDate	2025-03-14
AnnouncementXML	Submission_2025-03-14_12:29:44.057.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Lisa Jenkins
SpeciesList	scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationList	Carbamidomethyl; Oxidation
Instrument	Orbitrap Fusion; Orbitrap Fusion Lumos; Orbitrap Exploris 480

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-06-14 09:00:24	ID requested
⏵ 1	2025-03-14 12:29:44	announced

Publication List

Sun Y, Jenkins LM, El Touny LH, Zhu L, Yang X, Jo U, Escobedo L, Maity TK, Saha LK, Uribe I, Saha S, Takeda S, Leung AKL, Cheng K, Pommier Y, Flap endonuclease 1 repairs DNA-protein cross-links via ADP-ribosylation-dependent mechanisms. Sci Adv, 11(2):eads2919(2025) [pubmed]

Sun Y, Jenkins LM, El Touny LH, Zhu L, Yang X, Jo U, Escobedo L, Maity TK, Saha LK, Uribe I, Saha S, Takeda S, Leung AKL, Cheng K, Pommier Y, Flap endonuclease 1 repairs DNA-protein cross-links via ADP-ribosylation-dependent mechanisms. Sci Adv, 11(2):eads2919(2025) [pubmed]

Keyword List

submitter keyword: DNA-protein crosslink, formaldehyde DNA-protein crosslink, In vivo complex of enzyme assay, DPC composition

submitter keyword: DNA-protein crosslink, formaldehyde DNA-protein crosslink, In vivo complex of enzyme assay, DPC composition

Contact List

Lisa Jenkins
contact affiliation	NCI, NIH
contact email	jenkinsl@mail.nih.gov
lab head
Lisa Jenkins
contact affiliation	NCI
contact email	jenkinsl@mail.nih.gov
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v08/MSV000095039/

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v08/MSV000095039/