PXD053081

PXD053081 is an original dataset announced via ProteomeXchange.

Title	C57BL/6J mouse ovary,4DLabelfree quantitative protein sets from 6 mouse ovarian tissue samples (2 groups, 3 replicates)
Description	The ovarian tissues of 3 mice aged 3 months in the control group and the hyperhomocysteinemia group were selected for advanced 4D Laber-free quantitative proteomic analysis. According to 4D Laber-free quantitative proteomics analysis, we successfully quantified 56,611 peptides and identified 5,764 quantifiable proteins. Principal component analysis (PCA) highlights the extraordinary quantitative repeatability between biological replicas. Subsequently, we screened for differentially expressed proteins (DEPs) (P <0.05, multiple change (FC) >1.5). The results showed that there were 317 up-regulated and 113 down-regulated proteins.
HostingRepository	PRIDE
AnnounceDate	2025-05-07
AnnouncementXML	Submission_2025-05-06_19:37:42.504.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Lu Wang
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2024-06-13 08:22:10	ID requested
⏵ 1	2025-05-06 19:37:43	announced

10.1016/j.isci.2024.111241;

Wang L, Gao J, Ma J, Sun J, Wang Y, Luo J, Wang Z, Wang H, Li J, Yang D, Wang J, Hu R, Effects of hyperhomocysteinemia on follicular development and oocytes quality. iScience, 27(11):111241(2024) [pubmed]

submitter keyword: 4D Laber-free quantitative proteomics,C57BL/6J mouse, ovary

Rong Hu
contact affiliation	Reproductive Medicine Center, General Hospital of Ningxia Medical University, Ningxia, China
contact email	HuR@nyfy.com.cn
lab head
Lu Wang
contact affiliation	Ningxia Medical University
contact email	wl011542@163.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD053081

PRIDE project URI

• PRIDE
  1. PXD053081
     1. Label: PRIDE project
     2. Name: C57BL/6J mouse ovary,4DLabelfree quantitative protein sets from 6 mouse ovarian tissue samples (2 groups, 3 replicates)