PXD053081 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | C57BL/6J mouse ovary,4DLabelfree quantitative protein sets from 6 mouse ovarian tissue samples (2 groups, 3 replicates) |
Description | The ovarian tissues of 3 mice aged 3 months in the control group and the hyperhomocysteinemia group were selected for advanced 4D Laber-free quantitative proteomic analysis. According to 4D Laber-free quantitative proteomics analysis, we successfully quantified 56,611 peptides and identified 5,764 quantifiable proteins. Principal component analysis (PCA) highlights the extraordinary quantitative repeatability between biological replicas. Subsequently, we screened for differentially expressed proteins (DEPs) (P <0.05, multiple change (FC) >1.5). The results showed that there were 317 up-regulated and 113 down-regulated proteins. |
HostingRepository | PRIDE |
AnnounceDate | 2025-05-07 |
AnnouncementXML | Submission_2025-05-06_19:37:42.504.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Lu Wang |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | No PTMs are included in the dataset |
Instrument | timsTOF Pro |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-06-13 08:22:10 | ID requested | |
⏵ 1 | 2025-05-06 19:37:43 | announced | |
Publication List
10.1016/j.isci.2024.111241; |
Wang L, Gao J, Ma J, Sun J, Wang Y, Luo J, Wang Z, Wang H, Li J, Yang D, Wang J, Hu R, Effects of hyperhomocysteinemia on follicular development and oocytes quality. iScience, 27(11):111241(2024) [pubmed] |
Keyword List
submitter keyword: 4D Laber-free quantitative proteomics,C57BL/6J mouse, ovary |
Contact List
Rong Hu |
contact affiliation | Reproductive Medicine Center, General Hospital of Ningxia Medical University, Ningxia, China |
contact email | HuR@nyfy.com.cn |
lab head | |
Lu Wang |
contact affiliation | Ningxia Medical University |
contact email | wl011542@163.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD053081 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD053081
- Label: PRIDE project
- Name: C57BL/6J mouse ovary,4DLabelfree quantitative protein sets from 6 mouse ovarian tissue samples (2 groups, 3 replicates)