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PXD053081

PXD053081 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleC57BL/6J mouse ovary,4DLabelfree quantitative protein sets from 6 mouse ovarian tissue samples (2 groups, 3 replicates)
DescriptionThe ovarian tissues of 3 mice aged 3 months in the control group and the hyperhomocysteinemia group were selected for advanced 4D Laber-free quantitative proteomic analysis. According to 4D Laber-free quantitative proteomics analysis, we successfully quantified 56,611 peptides and identified 5,764 quantifiable proteins. Principal component analysis (PCA) highlights the extraordinary quantitative repeatability between biological replicas. Subsequently, we screened for differentially expressed proteins (DEPs) (P <0.05, multiple change (FC) >1.5). The results showed that there were 317 up-regulated and 113 down-regulated proteins.
HostingRepositoryPRIDE
AnnounceDate2025-05-07
AnnouncementXMLSubmission_2025-05-06_19:37:42.504.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterLu Wang
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-06-13 08:22:10ID requested
12025-05-06 19:37:43announced
Publication List
10.1016/j.isci.2024.111241;
Wang L, Gao J, Ma J, Sun J, Wang Y, Luo J, Wang Z, Wang H, Li J, Yang D, Wang J, Hu R, Effects of hyperhomocysteinemia on follicular development and oocytes quality. iScience, 27(11):111241(2024) [pubmed]
Keyword List
submitter keyword: 4D Laber-free quantitative proteomics,C57BL/6J mouse, ovary
Contact List
Rong Hu
contact affiliationReproductive Medicine Center, General Hospital of Ningxia Medical University, Ningxia, China
contact emailHuR@nyfy.com.cn
lab head
Lu Wang
contact affiliationNingxia Medical University
contact emailwl011542@163.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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