PXD053078

PXD053078 is an original dataset announced via ProteomeXchange.

Title	TBCK, PPP1R21, and C12orf4-interaction AP-MS
Description	To indentify the interaction protein of TBCK, PPP1R21, and C12orf4 by purification of flagg-tagged ones coupled mass spectrum
HostingRepository	PRIDE
AnnounceDate	2026-03-02
AnnouncementXML	Submission_2026-03-01_16:06:44.415.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Wang Yalan
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2024-06-13 06:39:21	ID requested
⏵ 1	2026-03-01 16:06:46	announced

Wang Y, Xu X, Cao X, He H, Qin Y, Deng T, Zhang Z, Wu L, Wang C, Wang H, TBCK syndrome pathogenesis: the TBCK-PPP1R21-C12orf4 complex regulating RAB5-dependent endo-lysosomal homeostasis. Sci Bull (Beijing), ():(2025) [pubmed]

10.1016/j.scib.2025.10.034;

submitter keyword: TBCK, and C12orf4-interaction AP-MS, PPP1R21

Hongyan Wang
contact affiliation	Fudan university
contact email	wanghy@fudan.edu.cn
lab head
Wang Yalan
contact affiliation	Fudan Universtiy
contact email	w_yalan@126.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/03/PXD053078

PRIDE project URI

• PRIDE
  1. PXD053078
     1. Label: PRIDE project
     2. Name: TBCK, PPP1R21, and C12orf4-interaction AP-MS