PXD053029

PXD053029 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	YTHDC1 lactylation promotes RCC progression by regulating phase-separation to enhance the stabilities of BCL2 and E2F2 mRNAs
Description	To obtain the global landscape of lactylation in hypoxia-treated RCC cells, we treated cells with 24 h hypoxia to induce maximum amount of hyperlactylated proteins and performed proteome and lactylome detection upon ACHN cells. Presented here is the raw data for the lactylome.
HostingRepository	PRIDE
AnnounceDate	2025-07-18
AnnouncementXML	Submission_2025-07-17_19:35:28.336.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	yuangui tang
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	lactic acid
Instrument	timsTOF Pro

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-06-11 23:47:29	ID requested
⏵ 1	2025-07-17 19:35:28	announced

Publication List

10.1016/J.MOLCEL.2025.06.017;

10.1016/J.MOLCEL.2025.06.017;

Keyword List

submitter keyword: BCL2, E2F2, YTHDC1,Lactylation, phase separation, renal cancer

submitter keyword: BCL2, E2F2, YTHDC1,Lactylation, phase separation, renal cancer

Contact List

junfang zheng
contact affiliation	Dr Junfang Zheng, Beijing Key Laboratory of Cancer Invasion and Metastasis Research, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China (lab head)
contact email	yuanguitang@outlook.com
lab head
yuangui tang
contact affiliation	Capital Medical University
contact email	yuanguitang@outlook.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/07/PXD053029
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/07/PXD053029

PRIDE project URI

Repository Record List

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