PXD052935 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Cysteine capping with CAM reagent |
Description | CAM reagent was synthesized and used to uniquely convert cysteine residues, under mild conditions, into trypsin-recognsable sites. We apply this cysteine-capping methodology in the identification of missense variants in HCT-15 cell lines.2-bromoethylamine (BEA)was used as controls, for cysteine capping and subjected to similar trypsin treatment. |
HostingRepository | PRIDE |
AnnounceDate | 2025-03-13 |
AnnouncementXML | Submission_2025-03-13_06:06:26.079.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Samuel Ofori |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Orbitrap Eclipse |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-06-07 12:10:53 | ID requested | |
⏵ 1 | 2025-03-13 06:06:26 | announced | |
Publication List
10.1039/d4cc01583e; |
Ofori S, Desai HS, Shikwana F, Boatner LM, Dominguez Iii ER, Castell, รณ, n JO, Backus KM, Generating cysteine-trypsin cleavage sites with 2-chloroacetamidine capping. Chem Commun (Camb), 60(67):8856-8859(2024) [pubmed] |
Keyword List
submitter keyword: CAM,cysteine capping, aminoethylation |
Contact List
Dr Keriann Marie Backus |
contact affiliation | Biological Chemistry, University of California Los Angeles, United States |
contact email | kbackus@mednet.ucla.edu |
lab head | |
Samuel Ofori |
contact affiliation | UCLA |
contact email | sofori@mednet.ucla.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/03/PXD052935 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD052935
- Label: PRIDE project
- Name: Cysteine capping with CAM reagent